Former Directors
| Sl No | Name | Period |
| 1 | Dr. Kesavapilla M N | 1947 to 31-03-1969 |
| 2 | Dr. Sreedharan N | 01-04-1969 to 28-02-1978 |
| 3 | Dr. Sankaranarayanan M S | 01-03-1978 to 31-07-1983 |
| 4 | Dr. Raman C A | 01-08-1983 to 31-03-1986 |
| 5 | Dr. Brahmadathan Namboodiri V M | 01-04-1986 to 23-04-1997 |
| 6 | Dr. Vasudeva Sharma N | 24-04-1997 to 30-04-1998 |
| 7 | Dr. Premlal P R | 01-05-1998 to 28-02-2001 |
| 8 | Dr. Chandramathi Amma C | 01-03-2001 to 31-05-2002 |
| 9 | Dr. Sreenivasan K P | 01-06-2002 to 31-12-2004 |
| 10 | Dr. Ramabhadran R | 01-01-2005 to 31-12-2006 |
| 11 | Dr. Mukundan P V | 01-01-2007 to 31-01-2007 |
| 12 | Dr. Anitha Jacob | 01-02-2007 to 28-02-2019 |
| 13 | Dr. Preeya K S | 01-03-2019 (continuing) |